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Prevention of the Infected Fracture: Evidence-Based Strategies for Success!

PMID: 31083141 (view PubMed database entry)
DOI: 10.1097/bot.0000000000001469 (read at publisher's website )

Cyril Mauffrey, David J Hak, David Rojas, Kent Doan, Brendan R Southam, Michael T Archdeacon, Martin Boyer, Michael McKee, Peter V Giannoudis, Emil H Schemitsch,

Department of Surgery, Western University, London, ON, Canada.

There is a significant burden of disease associated with infected fractures, and their management is challenging. Prevention of infection after musculoskeletal trauma is essential because treatment of an established infection continues to be a major obstacle. Despite the need for evidence-based decision making, there is a lack of consensus around strategies for prevention and surgical management of the infected fracture. The current evidence for the prevention of the infected fracture is reviewed here with a focus on evidence for antibiotic therapy and debridement, the induced membrane technique, management of soft-tissue defects, patient optimization, and adjuncts to prevent infection.

J Orthop Trauma (Journal of orthopaedic trauma)
[2019, 33 Suppl 6:S1-S5]

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