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'Just 17 if you know what I mean' … but what do we really mean to say about Th17 immunity?

PMID: 30873603 (view PubMed database entry)
DOI: 10.1111/imm.13055 (read at publisher's website )

Daniel M Altmann,

Department of Medicine, Imperial College London, London, UK.

Th17-derived IL-17 might be considered the archetypal pro-inflammatory cytokine of adaptive immunity, to be targeted by new therapeutics for alleviation of autoimmune and inflammatory disease. However, the IL-17 family of cytokines is produced by diverse innate and adaptive cells, including Th17, Tc17, ILC3, NK cells and γδ T-cells. These responses are appreciated to underpin diverse aspects of protective, physiological immunity, from dialogue with the gut microbiota to bacterial and fungal immunity in the lung.

Immunology (Immunology)
[2019, 156(4):297-298]

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