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Mediastinal desmoplastic small round cell tumor.

PMID: 33126354 (view PubMed database entry)
DOI: 10.1097/md.0000000000022921 (read at publisher's website )
PMCID: PMC7598786 (free full text version available)

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Dacheng Jin, Meng Chen, Bing Wang, Yunjiu Gou,

<h4>Rationale</h4>Desmoplastic small round cell tumor (DSRCT) is a rare distinct tumor with a high-grade malignancy.<h4>Patient concerns</h4>A 51-year-old male visited a local hospital in April 2016 complaining of shortness of breath, chest tightness and pain, and exhibited significant swelling in both sides of the chest.<h4>Diagnoses</h4>CT demonstrated thoracic symmetry and no abnormalities were observed in the soft tissues of the ribs and the chest wall. A general observation of CT-guided puncture biopsy revealed 2 stripes of gray and grayish-white puncture tissues of 0.5 and 1 cm in length, respectively, and 0.1 cm in diameter. These results preliminarily suggested a (mediastinum) malignant small round cell tumor.<h4>Intervention</h4>Given the progression of the disease, the chemotherapy regimen, consisting of ifosfamide and etoposide, was altered during the course and radiotherapy (total of 70 Gy of mediastinal Y field radiation) was conducted.<h4>Outcomes</h4>The patient and his family declined further treatment. Through follow-up, the total survival period was determined as 17 months.<h4>Lessons</h4>DSRCT is a rare interstitial malignant tumor. Effective cytoreduction combined with comprehensive therapies could achieve partial remission or prolong the survival of patients.

Medicine (Baltimore) (Medicine)
[2020, 99(44):e22921]

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