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How to Explore Fetal Sacral Agenesis Without Open Dysraphism: Key Prenatal Imaging and Clinical Implications.

PMID: 29377253 (view PubMed database entry)
DOI: 10.1002/jum.14522 (read at publisher's website )

Nicolas Mottet, Yann Chaussy, Frederic Auber, Fabien Guimiot, Francine Arbez-Gindre, Didier Riethmuller, CĂ©lia Cretolle, Alexandra Benachi,

The estimated prevalence of fetal caudal dysgenesis is 1 per 100,000 births. The functional prognosis of sacral agenesis is dominated by the large spectrum of associated caudal malformations. Except for cases associated with hydrocephalus secondary to open spinal dysraphism or chromosomal anomalies, association with mental deficiency is rare. We propose a systematic prenatal approach to cases of fetal sacral agenesis based on 9 etiologic items: clinical context, type of sacral dysgenesis, associated spinal cord malformations, mobility of lower limbs, investigation of the presacral region, analysis of the gastrointestinal tract, analysis of the genitourinary tract, associated vertebral defects, and cytogenetic analysis.

J Ultrasound Med (Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine)
[2018, 37(7):1807-1820]

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